Lactic Acid Polymers as Biodegradable Carriers of Fluoroquinolones: An In Vitro Study
AUTOR(ES)
Kanellakopoulou, Kyriaki
FONTE
American Society for Microbiology
RESUMO
A biodegradable polymer of dl-dilactide that facilitates release of ciprofloxacin or pefloxacin at levels exceeding MICs for the causative microorganisms of chronic osteomyelitis is described. Duration and peak of release were found to depend on the molecular weight of the polymer. Its characteristics make it promising for treating chronic bone infections.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=89192Documentos Relacionados
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