Leishmania major Promastigotes Inhibit Dendritic Cell Motility In Vitro
AUTOR(ES)
Jebbari, Heather
FONTE
American Society for Microbiology
RESUMO
Using an in vitro transwell migration assay, we have demonstrated that products secreted by Leishmania major promastigotes inhibit the motility of dendritic cells (DC) by up to 93%. Inhibition was dose dependent and reversible. By inhibiting DC migration in vivo, L. major may therefore subvert DC from their potentially protective role during leishmaniasis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=127657Documentos Relacionados
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