Leishmania (Viannia) lainsoni: occurrence of intracellular promastigote forms in vivo and in vitro
AUTOR(ES)
Corrêa, José R, Soares, Maurilio J
FONTE
Memórias do Instituto Oswaldo Cruz
DATA DE PUBLICAÇÃO
2006-12
RESUMO
Experimental chronic (45-day-old) skin lesion in hamster hind foot induced by Leishmania (Viannia) lainsoni infection showed the presence of promastigote forms in the tissue, inside parasitophorous vacuoles, as assessed by transmission electron microscopy. Experimental in vitro interaction (24 and 48 h) between Leishmania (V.)lainsoni and J774-G8 macrophage cells also demonstrated the same profile. This morphological aspect is unusual, since in this parasite genus only amastigote forms have been described as the resistant and obligate intracellular forms.
Documentos Relacionados
- Leishmania (Viannia) lainsoni (Kinetoplastida: Trypanosomatidae), a divergent Leishmania of the Viannia subgenus: a mini review
- Ação leishmanicida in vitro da miltefosine em formas promastigotas de Leishmania (Leishmania) amazonensis, Leishmania (Viannia) guyanensis, Leishmania (Viannia) braziliensis e estudo in vivo de sua eficáciano tratamento da leishmaniose cutânea experimental
- Cisteína-proteinases em promastigotas de Leishmania (Viannia) braziliensis.
- Polymerase chain reaction-based method for the identification of Leishmania (Viannia) braziliensis and Leishmania (Viannia) guyanensis in mucosal tissues conserved in paraffin
- In vitro and in vivo activity of meglumine antimoniate produced at Farmanguinhos-Fiocruz, Brazil, against Leishmania (Leishmania) amazonensis, L (L.) chagasi and L (Viannia) braziliensis
