Lentiviral Transduction of Dendritic Cells Confers Protective Antiviral Immunity In Vivo
AUTOR(ES)
Zarei, Shohreh
FONTE
American Society for Microbiology
RESUMO
Control of a viral infection in vivo requires a rapid and efficient cytotoxic-T-lymphocyte response. We demonstrate that lentivirus-mediated introduction of antigen in dendritic cells confers a protective antiviral immunity in vivo in a lymphocytic choriomeningitis virus model. Therefore, lentiviral vectors may be excellent vaccine candidates for viral infections.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=434082Documentos Relacionados
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