Localization of the streptococcal C5a peptidase to the surface of group A streptococci.
AUTOR(ES)
O'Connor, S P
RESUMO
Immunofluorescent staining was used to determine that the streptococcal C5a peptidase (SCP) exists as a cell surface antigen on group A streptococci. The ability of hyperimmune serum to neutralize cell-associated SCP activity provided further evidence for the location of SCP. Quantification of SCP during growth in vitro by indirect enzyme-linked immunosorbent assay showed that approximately 90% of the measurable antigen is cell bound.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=260894Documentos Relacionados
- Conservation of the C5a peptidase genes in group A and B streptococci.
- Virulent human strains of group G streptococci express a C5a peptidase enzyme similar to that produced by group A streptococci.
- Similarity between the group B and A streptococcal C5a peptidase genes.
- Antibody against Surface-Bound C5a Peptidase Is Opsonic and Initiates Macrophage Killing of Group B Streptococci
- C5a peptidase alters clearance and trafficking of group A streptococci by infected mice.
