Long-Term Predictive Value of a Single Cytomegalovirus (CMV) DNA PCR Assay for CMV Disease in Human Immunodeficiency Virus-Infected Patients
AUTOR(ES)
Walmsley, Sharon
FONTE
American Society for Microbiology
RESUMO
Universal prophylaxis with oral ganciclovir is not cost-effective for the prevention of cytomegalovirus (CMV) disease in human immunodeficiency virus infection. For a preemptive strategy to be considered, patients at highest risk for CMV disease need to be easily and accurately identified. In this study, the sensitivity, specificity, positive predictive value, and negative predictive value of a single CMV DNA PCR assay for the subsequent development of CMV disease were 0.75, 0.89, 0.75, and 0.89, respectively.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=124854Documentos Relacionados
- Long-term treatment of human immunodeficiency virus-infected cells with antisense oligonucleotide phosphorothioates.
- Quantitation of cytomegalovirus (CMV) DNA in leukocytes of human immunodeficiency virus-infected subjects with and without CMV disease by using PCR and the SHARP Signal Detection System.
- Diagnostic value of amplification of human cytomegalovirus DNA from gastrointestinal biopsies from human immunodeficiency virus-infected patients.
- PCR enzyme-linked immunosorbent assay for diagnosis of leishmaniasis in human immunodeficiency virus-infected patients.
- Limited value of PCR for detection of Toxoplasma gondii in blood from human immunodeficiency virus-infected patients.