Longitudinal Studies of Neutralizing Antibody Responses to Rotavirus in Stools and Sera of Children following Severe Rotavirus Gastroenteritis

AUTOR(ES)

Coulson, Barbara S.

FONTE

American Society for Microbiology

RESUMO

Rotavirus-neutralizing antibody responses in sera and stools of children hospitalized with rotavirus gastroenteritis and then monitored longitudinally were optimally detected by using local rotavirus strains. Stool responses were highest on days 5 to 8 after the onset of diarrhea. Longitudinal monitoring suggested that serum neutralizing antibody responses were a more useful measure of severely symptomatic rotavirus infection than stool responses but that stool antibody responses may be a useful measure of rotavirus immunity.

Documentos Relacionados

• Comparison of serum and mucosal antibody responses following severe acute rotavirus gastroenteritis in young children.
• Homotypic serum antibody responses to rotavirus proteins following primary infection of young children with serotype 1 rotavirus.
• Neutralizing antibodies to heterologous animal rotavirus serotypes 5, 6, 7, and 10 in sera from Ecuadorian children.
• Neutralizing antibody immune response in children with primary and secondary rotavirus infections.
• Prevalence of Neutralizing Antibodies against Different Rotavirus Serotypes in Children with Severe Rotavirus-Induced Diarrhea and Their Mothers