Loss of the Sigma Activity of RNA Polymerase of Bacillus subtilis during Sporulation
AUTOR(ES)
Linn, Thomas G.
RESUMO
The activity of the sigma subunit of the RNA polymerase of Bacillus subtilis decreases markedly during the first 2 hr of sporulation. Moreover, sigma activity remains deficient throughout the sporulation process and in dormant spores. The time course of changes in RNA polymerase during sporulation indicates that alterations in the core of RNA polymerase occur after the loss of sigma activity. Core RNA polymerase purified after the second and before the ninth hour of sporulation fails to respond to vegetative sigma subunit in vitro and contains variable amounts of a 110,000-dalton polypeptide in place of the β′ subunit. Core RNA polymerase purified from dormant spores has a subunit structure indistinguishable from vegetative core enzyme.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=433614Documentos Relacionados
- Sigma Factor Displacement from RNA Polymerase during Bacillus subtilis Sporulation
- Spo0A binds to a promoter used by sigma A RNA polymerase during sporulation in Bacillus subtilis.
- Temporal regulation and forespore-specific expression of the spore photoproduct lyase gene by sigma-G RNA polymerase during Bacillus subtilis sporulation.
- Genetic analysis of RNA polymerase-promoter interaction during sporulation in bacillus subtilis.
- A mutation in P23, the first gene in the RNA polymerase sigma A (sigma 43) operon, affects sporulation in Bacillus subtilis.