Lymphokine-activated-killer-mediated lysis of cells infected with typhus group rickettsiae can be inhibited by OKT3 monoclonal antibody.

AUTOR(ES)

Carl, M

RESUMO

We examined the ability of monoclonal antibodies directed against lymphocyte surface antigens to block the lysis of typhus group rickettsia-infected cells by lymphokine-activated killer effectors. Lysis was significantly inhibited by OKT3 monoclonal antibody but not by OKT4 or OKT8 monoclonal antibody.

Documentos Relacionados

• Recognition of typhus group rickettsia-infected targets by human lymphokine-activated killer cells.
• Does OKT3 monoclonal antibody react with an antigen-recognition structure on human T cells?
• Selective blockade of human natural killer cells by a monoclonal antibody.
• Active Lymphocytic Myocarditis Treated with Murine OKT3 Monoclonal Antibody: in a Patient Presenting with Intractable Ventricular Tachycardia
• Infections in Patients Receiving OKT3 Monoclonal Antibody for Cardiac Rejection: Results of a Small Clinical Trial