Maternal immunization with gametocyte antigens as a means of providing protective immunity against Eimeria maxima in chickens.

AUTOR(ES)

Wallach, M

RESUMO

In the present study, we wished to demonstrate the ability of surface gametocyte antigens to induce protective immunity against Eimeria maxima infections in chickens. In order to accomplish this goal, we employed maternal immunization as a means of providing large amounts of specific antibodies to offspring chicks. Upon challenge with sporulated E. maxima oocysts, chicks from hens immunized with affinity-purified gametocyte antigens showed greatly reduced oocyst production compared with chicks from sham-immunized hens. These results suggest that maternal immunization with gametocyte antigens can be used as a means to provide transmission-blocking immunity against E. maxima infections.

Documentos Relacionados

• Passive immunization of chickens against Eimeria maxima infection with a monoclonal antibody developed against a gametocyte antigen.
• Protective Immunity against Eimeria acervulina following In Ovo Immunization with a Recombinant Subunit Vaccine and Cytokine Genes
• Maternal transmission of immunity to Eimeria maxima: western blot analysis of protective antibodies induced by infection.
• Antigenic Diversity in Eimeria maxima and the Influence of Host Genetics and Immunization Schedule on Cross-Protective Immunity
• Nasal Immunization with Homogenate and Peptide Antigens Induces Protective Immunity against Trichinella spiralis