Maturation of the ileal epithelium in the young rat.
AUTOR(ES)
Carlile, A E
RESUMO
Normal maturation in the rat ileal epithelium (ileal 'closure') occurs between 18 and 21 days, probably by a process of cellular replacement. A single dose of cortisone acetate induced a precocious ileal 'closure' within 6 days. The morphological changes observed were similar to those seen during normal 'closure'. Morphometric measurements made of ileal villi during both normal and induced 'closure' suggest that there was a gradual change in the type of cells produced by the crypt. This was perhaps related to the duration of exposure of the cryptal cells to the 'closure' stimulus. Ten days after cortisone acetate treatment vacuolated cells were again seen on the villus in some animals. The variation in their distribution on the villus was perhaps due to differing rates at which the villi had recommenced pinocytosis because of the physiological state of the animal. A single dose of corticosterone failed to promote any morphological changes indicative of ileal 'closure' when observed at the electron microscope level.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1171827Documentos Relacionados
- Maturation in the ferret ileal epithelium and the effect of cortisone acetate.
- Cell renewal of oral mucosal epithelium of the rat.
- Laser induced phagocytosis in the pigment epithelium of the Hunter dystrophic rat.
- Maturation of the respiratory response to acute hypoxia in the newborn rat.
- Glucocorticoids accelerate fetal maturation of the epidermal permeability barrier in the rat.