Measurement of thrombopoiesis in rabbits using 75selenomethionine
AUTOR(ES)
Evatt, Bruce L.
RESUMO
Incorporation of 75selenomethionine (75SeM) has been used to study platelet production in rabbits. Radioactivity of platelets was low after the intravenous administration of 75SeM and rose to a maximum approximately 3 days after administration. Platelet radioactivity was independent of concurrent plasma levels. The life span of rabbit platelets, as estimated with this technique, was 4-5 days. In vivo reutilization of 75SeM previously incorporated into plasma proteins was not detected. In vitro incorporation of 75SeM by platelets in platelet-rich plasma was not demonstrated.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=535733Documentos Relacionados
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