Mechanism of antibody-mediated viral clearance in immunotherapy of respiratory syncytial virus infection of cotton rats.

AUTOR(ES)

Prince, G A

RESUMO

Antibody-mediated clearance of respiratory syncytial virus from cotton rat pulmonary tissues occurs in the absence of complement and in the absence of the Fc portion of the immunoglobulin G molecule, suggesting that complement-independent, cell-independent neutralization is the major mechanism of clearance.

Documentos Relacionados

• Effectiveness of topically administered neutralizing antibodies in experimental immunotherapy of respiratory syncytial virus infection in cotton rats.
• Respiratory syncytial virus infection in cyclophosphamide-treated cotton rats.
• Quantitative aspects of passive immunity to respiratory syncytial virus infection in infant cotton rats.
• Mechanisms of immunity to respiratory syncytial virus in cotton rats.
• Bovine respiratory syncytial virus protects cotton rats against human respiratory syncytial virus infection.