Mengovirus-Induced Cytopathic Effect in L-Cells: Protective Effect of Interferon

AUTOR(ES)
RESUMO

The effect of interferon on mengovirus-induced cytopathic effect (CPE) in L cells, the cut-off of host-cell protein synthesis, and production of mature virus were found to be dependent on the concentration of interferon. CPE and inhibition of host protein synthesis were not affected until the concentration of interferon was increased 100-fold over that required to reduce viral yields by 90%.

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