Methylxanthine-Induced Escalation: A Propagated Wave Phenomenon Observed in Skeletal Muscle Developing in Culture
AUTOR(ES)
Coleman, Annette W.
RESUMO
Relatively low concentrations of methylxanthines increase spontaneous twitching in cultured muscle fibers; they also cause a second activity, escalation, which is the initiation and undiminished propagation of visible waves. The effect on twitching is abolished by depolarizing concentrations of K+ or by tetrodotoxin; the effect on escalation is not. Escalation is prevented by removal of external Ca++ or by the addition of tetracaine.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=426518Documentos Relacionados
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