Microbial and chemical transformations of some 12,13-epoxytrichothec-9,10-enes.
AUTOR(ES)
Claridge, C A
RESUMO
Resting cells of Streptomyces griseus, Mucor mucedo, and a growing culture of Acinetobacter calcoaceticus when mixed with compounds related to 12,13-epoxytrichothec-9-ene-4beta,15-diacetoxy-3alpha-ol(anguidine) produced a series of derivatives that were either partially hydrolyzed or selectively acylated. These derivatives showed marked differences in activities as assayed by antifungal and tissue culture cytotoxicity tests.
ACESSO AO ARTIGO
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