Microhabitats within Venomous Cone Snails Contain Diverse Actinobacteria▿ †
AUTOR(ES)
Peraud, Olivier
FONTE
American Society for Microbiology (ASM)
RESUMO
Actinomycetes can be symbionts in diverse organisms, including both plants and animals. Some actinomycetes benefit their host by producing small molecule secondary metabolites; the resulting symbioses are often developmentally complex. Actinomycetes associated with three cone snails were studied. Cone snails are venomous tropical marine gastropods which have been extensively examined because of their production of peptide-based neurological toxins, but no microbiological studies have been reported on these organisms. A microhabitat approach was used in which dissected tissue from each snail was treated as an individual sample in order to explore bacteria in the tissues separately. Our results revealed a diverse, novel, and highly culturable cone snail-associated actinomycete community, with some isolates showing promising bioactivity in a neurological assay. This suggests that cone snails may represent an underexplored reservoir of novel actinomycetes of potential interest for drug discovery.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2772445Documentos Relacionados
- Efficient oxidative folding of conotoxins and the radiation of venomous cone snails
- Revertants of a Transcription Termination Mutant of Yeast Contain Diverse Genetic Alterations
- Biogenic Formation of As-S Nanotubes by Diverse Shewanella Strains▿ †
- Serological Diversity Within a Terrestrial Ammonia-Oxidizing Population †
- Expression of multiple homeobox genes within diverse mammalian haemopoietic lineages.