Molecular archeology of L1 insertions in the human genome
AUTOR(ES)
Szak, Suzanne T
FONTE
BioMed Central
RESUMO
A detailed analysis of the anatomy and distribution of L1 elements in the human genome was carried out using a new computer program, TSDfinder, designed to identify transposon boundaries precisely. Conclusions: The sequence data give no indication that the creation of L1 structural variants depends on characteristics of the insertion locus.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=134481Documentos Relacionados
- More active human L1 retrotransposons produce longer insertions
- L1 Interaction Domains of Papillomavirus L2 Necessary for Viral Genome Encapsidation
- Molecular Characterization of IS1541 Insertions in the Genome of Yersinia pestis
- Self-assembly of human papillomavirus type 1 capsids by expression of the L1 protein alone or by coexpression of the L1 and L2 capsid proteins.
- Specific Inactivation of Inhibitory Sequences in the 5′ End of the Human Papillomavirus Type 16 L1 Open Reading Frame Results in Production of High Levels of L1 Protein in Human Epithelial Cells
