Molecular Characterization of the vanE Gene Cluster in Vancomycin-Resistant Enterococcus faecalis N00-410 Isolated in Canada

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

The vanE operon was characterized from Enterococcus faecalis N00-410 (MIC of vancomycin = 24 μg/ml). The organization of the vanE operon was identical to that of the vanC1 operon from Enterococcus gallinarum, with protein identities ranging from 46 to 63%. An open reading frame located downstream of the vanE operon showed significant homology to a number of integrase genes, all of which are located downstream of the chromosomal GMP synthase gene guaA.

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