Mutations in 23S rRNA in Helicobacter pylori Conferring Resistance to Erythromycin Do Not Always Confer Resistance to Clarithromycin
AUTOR(ES)
García-Arata, M. Isabel
FONTE
American Society for Microbiology
RESUMO
Mutations conferring resistance to erythromycin or clarithromycin in Helicobacter pylori were studied. Mutation A2142G was consistently associated with clarithromycin MIC of >256 μg/ml, whereas mutants carrying A2143G had MICs ranging from ≤0.016 to >256 μg/ml, suggesting that additional factors account for the observed multiple levels of resistance to clarithromycin.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=89082Documentos Relacionados
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