Mycosis fungoides and Kaposi’s sarcoma association in an HIV-negative patient
AUTOR(ES)
Bariani, Maria Carolina Prado Fleury, Fleury Júnior, Luiz Fernando Fróes, Ribeiro, Ana Maria Quinteiro, Carneiro, Siderley de Souza, Pereira, Tiago Arantes
FONTE
An. Bras. Dermatol.
DATA DE PUBLICAÇÃO
2016-10
RESUMO
Abstract The association of mycosis fungoides and kaposi’s sarcoma in HIV-negative patients is a rare phenomenon. The presence of human herpesvirus 8 (HHV-8) – associated with all forms of Kaposi’s sarcoma – has also been recently identified in mycosis fungoides lesions. However, a causal association between HHV-8 and the onset of mycosis fungoides has not been established yet. The present case reports a patient who developed Kaposi’s sarcoma lesions after a two-year UVB phototherapy to treat a mycosis fungoides. Negative immunohistochemistry staining for Kaposi’s sarcoma-associated herpesvirus in the initial mycosis fungoides lesions strengthens the absence of a link between Kaposi’s sarcoma-associated herpesvirus and mycosis fungoides. Immunosuppression caused by the lymphoma and prolonged phototherapy were probably the contribut ing factors for the onset of Kaposi’s sarcoma.
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