Neurospora crassa A mating-type region.
AUTOR(ES)
Glass, N L
RESUMO
The mating-type locus of the haploid filamentous fungus Neurospora crassa is a regulatory region that controls entry into the sexual cycle and prevents formation of mixed mating-type heterokaryons in the vegetative phase. The locus consists of alternative sequences called A and a. The A mating-type DNA sequence of Neurospora crassa is composed of a region of 5301 base pairs that has little similarity to the sequence present at the mating-type locus in an a mating-type strain. However, the sequences flanking the mating-type locus in the A haploid and a haploid genome are essentially identical. The region of the A mating-type sequence required for expression of the heterokaryon incompatibility and sexual functions has been localized to a single open reading frame (ORF) encoding a polypeptide of 288 amino acids. Sequence analysis of sterile, heterokaryon-compatible mutants reveals frameshift mutations in this same ORF. The putative 288-amino acid product has a region of similarity to the MAT alpha 1 polypeptide of Saccharomyces cerevisiae.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=54231Documentos Relacionados
- Neurospora crassa a mating-type region.
- Mutations of the a Mating-Type Gene in NEUROSPORA CRASSA
- Pseudohomothallism and Evolution of the Mating-Type Chromosome in Neurospora Tetrasperma
- Regulation of Mating and Meiosis in Yeast by the Mating-Type Region
- Regulation of yeast mating-type interconversion: feedback control of HO gene expression by the mating-type locus.
