New insights into a persistent problem — chlamydial infections
AUTOR(ES)
Morrison, Richard P.
FONTE
American Society for Clinical Investigation
RESUMO
Tissue tropism of clinical ocular and genital Chlamydia trachomatis strains is shown to be linked to the tryptophan synthase genotype. It is suggested that, in the presence of IFN-γ, which depletes available tryptophan, there exist unique host-parasite interactions that may contribute to persistent chlamydial infection.