Nocardia infections in congenitally athymic (nude) mice and in other inbred mouse strains.
AUTOR(ES)
Folb, P I
RESUMO
The mortality rate and histopathological features of Nocardia asteroides and Nocardia brasiliensis infections in congenitally athymic (nude) mice of ICR and C3H/eB origins were quite different from what we found for Swiss white mice and other inbred mouse strains (namely, C57/BL/6J, New Zealand Black, BALB/c, CBA/LAC, and C3H/eB). The immunocompetent littermates of the congenitally athymic mice occupied an intermediate position between their athymic siblings and Swiss white mice in terms of their responses to both these organisms. Macrophage ingestion and destruction of N. brasiliensis, as demonstrated by electron microscopy, was found to occur. The T-lymphocyte appears to be an essential component in normal mouse resistance to infection by both N. asteroides and N. brasiliensis.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=421255Documentos Relacionados
- Persistent Cryptosporidium infection in congenitally athymic (nude) mice.
- Trypanosoma rhodesiense infection in congenitally athymic (nude) mice.
- Infections of Congenitally Athymic (Nude) and Normal Mice with Avirulent and Virulent Strains of Venezuelan Encephalitis Virus
- Susceptibility of congenitally athymic (nude) mice to sporotrichosis.
- Infectious Agents in Immunodeficient Murine Models: Pathogenicity of Nocardia asteroides in Congenitally Athymic (Nude) and Hereditarily Asplenic (Dh/+) Mice
