Novel adjuvant action of lipopolysaccharides that possess mannose homopolysaccharides as O-specific polysaccharides on immune responses to nonimmunogenic autoantigens in mice.
AUTOR(ES)
Yokochi, T
RESUMO
The adjuvant action of various lipopolysaccharides on immune responses to syngeneic tissue extract in mice was examined. Only lipopolysaccharides possessing the linear mannose homopolysaccharides as O-specific polysaccharides exhibited definite adjuvant action on immune responses to the autoantigens. The intensity of this adjuvant activity of lipopolysaccharide from Klebsiella O3 seemed to be the strongest.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=258254Documentos Relacionados
- Genetic Determination of Enzymes Synthesizing O-Specific Sugars of Salmonella Lipopolysaccharides
- Structure of O-Specific Side Chains of Lipopolysaccharides from Yersinia pseudotuberculosis
- Augmented immunological activities of recombinant lipopolysaccharide possessing the mannose homopolymer as the O-specific polysaccharide.
- Binding of mannose-binding protein to Klebsiella O3 lipopolysaccharide possessing the mannose homopolysaccharide as the O-specific polysaccharide and its relation to complement activation.
- Protection of mice against Salmonella typhimurium with an O-specific polysaccharide-protein conjugate vaccine.
