Novel chiral ionic liquid (CIL) assisted selectivity enhancement to (L)-proline catalyzed asymmetric aldol reactions
AUTOR(ES)
Zhang, Long, Zhang, Haibo, Luo, Huadong, Zhou, Xiaohai, Cheng, Gongzhen
FONTE
Journal of the Brazilian Chemical Society
DATA DE PUBLICAÇÃO
2011-09
RESUMO
Melhoras significativas nos rendimentos químicos (até 88%), estereosseletividades (> 99:1) e excessos enantioméricos (até 98%) foram observadas em reações aldólicas assimétricas catalisadas por (L)-prolina, quando líquidos iônicos quirais baseados em prolina (CILs) foram usados como aditivos. Diferentes proporções de DMSO/H2O como solvente, e líquidos iônicos quirais (CILs) com cátions quirais com diferentes comprimentos de cadeia, foram investigados
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