On the application of knoevenagel condensation for the synthesis of benzylidene benzothiazine compounds and structural study
AUTOR(ES)
Souza, Ana Maria Alves de, Guarda, Vera Lucia de Miranda, Leite, Lúcia Fernanda Cavalcanti da Costa, Barbosa Filho, José Maria, Lima, Maria do Carmo Alves de, Galdino, Suely Lins, Pitta, Ivan da Rocha
FONTE
Química Nova
DATA DE PUBLICAÇÃO
2006-10
RESUMO
The synthesis and physico-chemical properties of new 6-acetylamino or 6-benzoyl-amino 2-benzylidene-4-methyl-4H-benzo[1,4]thiazin-3-ones and 6-benzoylamino or 6-nitro 2-benzylidene-4H-benzo[1,4]thiazin-3-ones are described. These benzylidene benzothiazine compounds were prepared by the Knoevenagel condensation with benzaldehydes. The configurations and conformations of benzylidene benzothiazine derivatives were optimised using the semi-empirical method AM1.
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