Origin of small RNA in von Magnus particles of influenza virus.
AUTOR(ES)
Nakajima, K
RESUMO
A clone of recombinant virus obtained from the cross between WSN and Hong Kong strains of influenza virus gave rise to progeny containing predominantly von Magnus particles. In the electropherogram of virus RNA, the P3 gene was markedly diminished, and a new species of RNA (extra RNA) was present in addition to eight gene segments. The origin of the extra RNA was studied by two-dimensional gel electrophoresis of T1 RNase-generated oligonucleotides. Four out of five large oligonucleotide spots present in the extra RNA matched to those contained by the P3 gene. It was concluded that the extra RNA was derived from the P3 gene probably by deletion. The possible origin of the spot which was present in the extra RNA but not in eight gene segments including P3 was discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=353274Documentos Relacionados
- Extra RNAs of von Magnus particles of influenza virus cause reduction of particular polymerase genes.
- The RNA of influenza virus.
- Synthesis of a small RNA in cells coinfected by standard and defective interfering particles of vesicular stomatitis virus.
- Characterization of the mRNA of influenza virus.
- Pathogenicity of influenza virus.