Oxygen Depletion-Induced Dormancy in Mycobacterium bovis BCG

AUTOR(ES)

Lim, Amanda

FONTE

American Society for Microbiology

RESUMO

Gradual depletion of oxygen causes the shift-down of aerobic growing Mycobacterium bovis BCG to an anaerobic synchronized state of nonreplicating persistence. The persistent culture shows induction of glycine dehydrogenase and α-crystallin-like protein and is sensitive to metronidazole.

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