P sequences of Drosophila subobscura lack exon 3 and may encode a 66 kd repressor-like protein.

AUTOR(ES)

Paricio, N

RESUMO

Several P homologous sequences have been cloned and sequenced from Drosophila subobscura. These sequences are located at the 85DE region of the O chromosome and at least three of them are organized in tandem. We have identified four copies which exhibit strong similarity between them. All of the isolated elements are truncated at the 5' and 3' ends. They have lost the inverted terminal repeats and exon 3, but maintain exons 0, 1 and 2. They are transcribed producing a polyadenylated RNA. The structure of these transcripts suggests that they are able to encode a 66 kd repressor-like protein, but not a functional transposase. We ask about the biological role of a potential repressor protein in this species.

Documentos Relacionados

• The maize repressor-like gene intensifier1 shares homology with the r1/b1 multigene family of transcription factors and exhibits missplicing.
• pen repeat sequences are GGN clusters and encode a glycine-rich domain in a Drosophila cDNA homologous to the rat helix destabilizing protein.
• Evolutionary conservation and predicted structure of the Drosophila extra sex combs repressor protein.
• Multicopy suppressors of phenotypes resulting from the absence of yeast VDAC encode a VDAC-like protein.
• Nucleotide sequence of the arrestin-like 49 Kd protein gene of Drosophila miranda.