Passive Immunity in Helicobacter-Challenged Neonatal Mice Conferred by Immunized Dams Lasts until Weaning
AUTOR(ES)
Corthésy-Theulaz, Irène
FONTE
American Society for Microbiology
RESUMO
The objective of this study was to examine the effect of breast-feeding by immunized dams on Helicobacter colonization in newborns. Urease-based immunization regimens failed to protect nursing pups against H. felis, whereas H. felis lysate-cholera toxin resulted in protection. This observation correlated with a high recognition of cell surface-expressed bacterial antigens by milk antibodies. Protection lasted until weaning, indicating that infection is maintained at undetectable levels by passive immunity but then resumes when breast-feeding stops.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=152048Documentos Relacionados
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