PEPTIDES REQUIRED FOR THE GROWTH OF LACTOBACILLUS BULGARICUS

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Jones, K. M. (The Rockefeller Institute, New York, N. Y.) and D. W. Woolley. Peptides required for the growth of Lactobacillus bulgaricus. J. Bacteriol. 83:797–801. 1962.—Lactobacillus bulgaricus 09 had an absolute requirement for growth for a suitable peptide, which was satisfied by trypsinized casein or hemoglobin. Digests of globin and the α and β chains derived from it showed similar activity to hemoglobin digests. Each of four highly purified peptides of different amino acid composition isolated from the α chain of globin had activity. Each active peptide had seven or more residues; smaller peptides were inactive. The requirement for L. bulgaricus was not one for strepogenin because some substances with strepogenin activity for L. casei were not active for L. bulgaricus.

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