Permeability of the human placenta in vivo to four non-metabolized hydrophilic molecules.
AUTOR(ES)
Bain, M D
RESUMO
1. Permeability of the human placenta to four permeants of different molecular size was measured at Caesarean section in seven normal full-term pregnancies. 2. Placental clearance for mannitol was 8.7 +/- 1.1 ml min-1 (mean +/- S.E.M.), lactulose 6.3 +/- 0.8, chromium ethylenediaminetetraacetic acid (CrEDTA) 3.7 +/- 0.5, and inulin 0.98 +/- 0.1. 3. The permeability data were analysed in terms of restricted diffusion through 'notional' water-filled pores and found to be incompatible with a single population of uniform pores.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1181787Documentos Relacionados
- Permeability of the boundary layers of Bdellovibrio bacteriovorus 109J and its bdelloplasts to small hydrophilic molecules.
- In vivo permeability of the human placenta to inulin and mannitol.
- Transport of solutes through cartilage: permeability to large molecules.
- Neisseria gonorrhoeae cell envelope: permeability to hydrophobic molecules.
- Detection of non-homology-containing heteroduplex molecules.