Pharmacodynamic Interaction of Doxycycline and Artemisinin in Plasmodium falciparum
AUTOR(ES)
Sponer, Ulrike
FONTE
American Society for Microbiology
RESUMO
Parallel in vitro tests, assessing the inhibition of schizont maturation, were conducted with 31 fresh isolates of Plasmodium falciparum from Thailand, using artemisinin, doxycycline, and combinations of both. The activities of artemisinin and doxycycline are obviously not correlated. Both compounds showed consistent synergism at 50% effective concentration (EC50), EC90, and EC99 levels.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=126969Documentos Relacionados
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