Pharmacokinetics of high-dose intravenous ciprofloxacin in young and elderly and in male and female subjects.
AUTOR(ES)
Shah, A
RESUMO
The effects of age and gender on the pharmacokinetics of high-dose intravenous ciprofloxacin in a healthy volunteer study were investigated. Plasma ciprofloxacin concentrations were higher in the elderly than in the young, and the pharmacokinetic parameters were not significantly different between the genders. Ciprofloxacin was well tolerated, with the majority of adverse events related to local reactions at the IV site.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=162672Documentos Relacionados
- Pharmacokinetic Profiles of High-Dose Intravenous Ciprofloxacin in Severe Sepsis
- High-dose intravenous methylprednisolone in rheumatoid arthritis.
- Comparative pharmacokinetics of low- and high-dose ticarcillin.
- Amikacin pharmacokinetics in patients receiving high-dose cancer chemotherapy.
- High-dose intravenous human immunoglobulin in polymyositis resistant to treatment.
