Phenotypic conversion of Pseudomonas aeruginosa in cystic fibrosis.
AUTOR(ES)
Fegan, M
RESUMO
Pseudomonas aeruginosa strains isolated from cystic fibrosis patients were tested for production of exoenzymes, sensitivity to pooled normal human serum, and colony morphology. Strains isolated from patients exhibiting a severe form of the disease were seen to produce a decreased range of exoenzymes, to show an increase in their serum sensitivity, and to be predominantly mucoid in colonial character compared with strains isolated from patients with a milder form of the disease. These results suggest that P. aeruginosa undergoes phenotypic changes with respect to exoenzyme secretion, serum sensitivity, and colony form as the clinical condition of the cystic fibrosis patient changes.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=267893Documentos Relacionados
- Mucoid conversion by phages of Pseudomonas aeruginosa strains from patients with cystic fibrosis.
- Cystic fibrosis. 1. Pseudomonas aeruginosa infection in cystic fibrosis and its management.
- Conversion of Pseudomonas aeruginosa to the phenotype characteristic of strains from patients with cystic fibrosis.
- Pseudomonas aeruginosa flagellar antibodies in patients with cystic fibrosis.
- Extrapulmonary sites of Pseudomonas aeruginosa in adults with cystic fibrosis.
