Polycistronic Effects of Catabolite Repression on the lac Operon
AUTOR(ES)
Silverstone, Allen E.
RESUMO
The catabolite repression caused by glucose and glucose-6-phosphate has been studied for both β-galactosidase and thiogalactoside transacetylase, the products of the operator proximal and distal cistrons of the lac operon, respectively. We find that both cistrons are affected coordinately by this form of repression. We also find that a single alteration at the lac promoter region is sufficient to abolish sensitivity to repression of both cistrons. From this, we conclude that there is only one target site for catabolite repression in the lac operon.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=251547Documentos Relacionados
- Regulation of lac Operon Expression: Reappraisal of the Theory of Catabolite Repression
- Corepressor System for Catabolite Repression of the lac Operon in Escherichia coli1
- Effect of catabolite repression on the mer operon.
- Transient Repression of the lac Operon
- Repression and catabolite repression of the lactose operon of Staphylococcus aureus.