Polymorphisms of the Fimbria fim3 Gene of Bordetella pertussis Strains Isolated in Canada

AUTOR(ES)

Tsang, Raymond S. W.

FONTE

American Society for Microbiology

RESUMO

The fim genes which code for the fimbria protective antigens present in both the inactivated whole-cell and acellular vaccines were analyzed in 86 Canadian Bordetella pertussis isolates. At least one of the novel mutations identified was found to involve a surface epitope that has been mapped by serum antibodies from infected or vaccinated subjects.

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