Polymyxin B Inactivation of Lipopolysaccharide in Vaccines of Gram-Negative Bacteria

AUTOR(ES)
RESUMO

Endotoxin activity in suspensions of Bordetella pertussis, Escherichia coli, Haemophilus influenzae, and Pseudomonas aeruginosa was often markedly decreased by polymyxin B. Polymyxin B treatment may be a means to reduce inflammatory reactivity of lipopolysaccharide in vaccines of gram-negative bacteria.

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