Porcine pituitary dynorphin: complete amino acid sequence of the biologically active heptadecapeptide.
AUTOR(ES)
Goldstein, A
RESUMO
The full primary structure of the very potent opioid peptide dynorphin, from porcine pituitary, has been determined. It is (H)Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln(OH). The synthetic peptide with this sequence behaves identically to natural dynorphin in a number of ways, and it has the same potency in the guinea pig ileum myenteric plexus--longitudinal muscle bioassay. The potency is accounted for by the first 13 residues.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=349228Documentos Relacionados
- Isolation and amino acid sequence analysis of a 4,000-dalton dynorphin from porcine pituitary.
- Complete amino acid sequence of beta-tubulin from porcine brain.
- Complete amino acid sequence of alpha-tubulin from porcine brain.
- The amino acid sequence of porcine thyrocalcitonin.
- Amino-Acid Sequence of Porcine Pepsin
