Precipitation of visna viral proteins by immune sera of rabbits and sheep.
AUTOR(ES)
Lin, F H
RESUMO
Eighteen polypeptides equivalent to 1.2 x 10(6) daltons of visna virus were specifically precipitated by immune sera from rabbits and sheep. The hyperimmunized rabbit antisera contained high concentrations of antibodies against p25 and p14, whereas the sera from sheep actively infected with visna virus showed a large quantity of anti-gp115 antibody. The results indicate that almost all the polypeptides reported previously (F. H. Lin, J. Virol. 25:207--214, 1978) are virus-specific components of visna. The presence of anti-gp115 antibody in sera of infected sheep may offer a simple and sensitive diagnostic procedure for visna.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=353187Documentos Relacionados
- Initial lentivirus-host interactions within lymph nodes: a study of maedi-visna virus infection in sheep.
- Limited protection of rabbits against infection with Treponema pallidum by immune rabbit sera.
- Formation of soluble immune complexes by complement in sera of patients with various hypocomplementemic states. Difference between inhibition of immune precipitation and solubilization.
- Antibodies Produced by Rabbits Immunized with Visna Virus
- Novel proteins of Plasmodium falciparum identified by differential immunoscreening using immune and patient sera.