Prednisolone inhibits phagocytosis by polymorphonuclear leucocytes via steroid receptor mediated events
AUTOR(ES)
Jones, Carolyn J. P.
RESUMO
Prednisolone, at concentrations between 2·78 × 10−6 M (1 μg/ml) and 1·39 × 10−8 M (5 × 10−3 μg/ml) exerts an inhibitory effect on the phagocytosis of latex particles by normal human polymorphonuclear leucocytes in vitro as assessed by electron microscopical analysis. This inhibition appears to be receptor-mediated, as it is dependent upon RNA and protein synthesis and is glucocorticoid specific.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1001061Documentos Relacionados
- Hydroxyapatite phagocytosis by human polymorphonuclear leucocytes.
- Observations on phagocytosis of urate crystals by polymorphonuclear leucocytes.
- Heparin inhibits phagocytosis by polymorphonuclear leukocytes.
- Yersinia pseudotuberculosis inhibits Fc receptor-mediated phagocytosis in J774 cells.
- Saliva inhibits the chemiluminescence response, phagocytosis, and killing of Staphylococcus epidermidis by polymorphonuclear leukocytes.
