Preparation and phytotoxicity of sorgoleone analogues

AUTOR(ES)

Barbosa, Luiz Cláudio de Almeida, Ferreira, Maria Lúcia, Demuner, Antonio Jacinto, Silva, Antonio Alberto da, Pereira, Rita de Cássia

FONTE

Química Nova

DATA DE PUBLICAÇÃO

2001-12

RESUMO

3,5-Dimethoxybenzylic alcohol was converted into the 2-acetoxy-5-methoxy-3-(pent-1-yl)-1,4-benzoquinone (12), in seven steps, with an overall yield of 14.6%. The natural quinone sorgoleone (1) was isolated from Sorghum bicolor and converted into the corresponding quinone (13) having a saturated side chain. The selective effects of these compounds (1, 12 and 13), at the dose of 5.6 mug of a.i./ g of substrate, on the growth of Cucumis sativus, Lactuca sativa, Desmodium tortuosum, Hyptis suaveolens and Euphorbia heterophylla were evaluated. All three compounds caused some inhibition on the root growth of the test plants (0.0-69.19%) with the aerial parts less affected. The results showed that the triene unit of the sorgoleone side chain is not essential for the phytotoxicity and also the synthetic quinone was as active as the natural product.

Documentos Relacionados

• Síntese e fitotoxicidade de benzopironas análogas ao alternariol
• Synthesis and Evaluation of the Phytotoxicity of News Butenolides Analogues of the Nostoclides.
• New efficient sulfurizing reagents for the preparation of oligodeoxyribonucleotide phosphorothioate analogues.
• Phytotoxicity of Perlatolic Acid and Derivatives
• Preparation of aromatic geraniol analogues via a Cu(I)-mediated Grignard coupling