Prevalência e diagnóstico laboratorial da infecção pelo vírus HTLV em gestantes de Mato Grosso do Sul, no período de 2002 a 2006

AUTOR(ES)
DATA DE PUBLICAÇÃO

2008

RESUMO

The Program for Pregnant Women Protection of Mato Grosso do Sul carried out the initial trial for the HTLV 1-2 infection in 155.807 pregnant women, between 2002 and 2006, by the means of ELISA technique in filter paper. Aiming to get knowledge about the HTLV behavior in face of the laboratorial tests used in the Program, a descriptive study was done in which 206 cases of HTLV were found (0,13%) that had their confirmation by the means of ELISA and Western Blot techniques in serum. From those 206 pregnant women, 13,1% had their diagnosis as indeterminate, 76,6% due to HTLV-1, 9,7% due to HTLV-2 and 1 case (0,4%) of mixed infection (HTLV 1 and 2). Concerning to the results obtained with the Western Blot technique, 54,0% presented 11 bands (4 ENV proteins and 7 GAG proteins), so that 72,9% of these cases refer to HTLV-1, reflecting a strong virus reaction to the proteins used in the test. The HTLV-2 showed an even weaker than that caused by the type 1 that had its most frequent combination as 2 ENV proteins with 1 GAG. Whereas it is a rare case, a mixed infection can probably be detected only in studies with great samples, like this one. The Program for Pregnant Women Protection of Mato Grosso do Sul follows the criteria for HTLV diagnosis recommended by the Ministry of Health. The prenatal initial trial is of great importance for the prevention of vertical transmission, besides the fact of making it possible to take preventive actions in order to avoid other manners of transmission.

ASSUNTO(S)

pré-natal prenatal ciencias da saude htlv htlv pregnant women mato grosso do sul mato grosso do sul gestante

ACESSO AO ARTIGO

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