Production of a Potent Vaccine from the Attenuated M-44 Strain of Coxiella burneti
AUTOR(ES)
Robinson, David M.
RESUMO
The attenuated M-44 strain of Coxiella burneti was heated to free it of adventitious agents that may have been present. Parallel titrations of the strain before and after heating indicated that the virulence for guinea pigs was markedly decreased. Guinea pigs immunized with the strain derived after heat treatment were protected from the effects of challenge with C. burneti in either phase I or II.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=380134Documentos Relacionados
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