Progenitors in motion: mechanisms of mobilization of endothelial progenitor cells
AUTOR(ES)
Tilling, Lindsey
FONTE
Blackwell Science Inc
RESUMO
Endothelial progenitor cells are a population of bone marrow-derived mononuclear cells thought to engage in endothelial repair and hence are considered potential therapeutic agents in many pathological conditions. The mechanism of their exit from the bone marrow to the circulation and damaged tissues, termed mobilization, has not been fully elucidated. Despite this, several pharmacological interventions have been shown to influence mobilization of these specialized cells. Here we review the current understanding of their mobilization.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2780273Documentos Relacionados
- Neurotrophins promote revascularization by local recruitment of TrkB+ endothelial cells and systemic mobilization of hematopoietic progenitors
- Intermediate Filaments in Motion: Observations of Intermediate Filaments in Cells Using Green Fluorescent Protein-VimentinV⃞
- Endothelial progenitor cells & translational research
- Anaphase chromatid motion: involvement of type II DNA topoisomerases.
- Endothelial progenitor cells and vascular endothelial growth factor in patients with Takayasu's arteritis