Prophage induction and inactivation by UV light.
AUTOR(ES)
Barnhart, B J
RESUMO
Analysis of the induction curves for UV light-irradiated Haemophilus influenzae lysogens and the distribution of pyrimidine dimers in a repair-deficient lysogen suggests that one dimer per prophage-size segment of the host bacterial chromosome is necessary as a preinduction event. The close correlations obtained prompted a renewed consideration of the possibility that direct prophage induction occurs when one dimer is stabilized within the prophage genome. The host excision-repair system apparently functions to reduce the probability of "stabilizing" within the prophage those dimers that are necessary for induction and inactivation. The presence of the inducible defective prophage in strain Rd depresses the inducibility of prophage HP1c1.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=354795Documentos Relacionados
- Genetic control of prophage induction in haemophilus influenzae after exposure to psoralen plus near-UV light.
- Photoreactivation of Escherichia coli reverses umuC induction by UV light.
- Pathogenesis of herpes simplex labialis: experimental induction of lesions with UV light.
- Synthesis of coronavirus mRNAs: kinetics of inactivation of infectious bronchitis virus RNA synthesis by UV light.
- Inactivation of Bacillus thuringiensis spores by ultraviolet and visible light.
