Protein flexibility: coordinate uncertainties and interpretation of structural differences

AUTOR(ES)

Rashin, Alexander A.

FONTE

International Union of Crystallography

RESUMO

Criteria for the interpretability of coordinate differences and a new method for identifying rigid-body motions and nonrigid deformations in protein conformational changes are developed and applied to functionally induced and crystallization-induced conformational changes.

Documentos Relacionados

• Glycerol effects on protein flexibility: a tryptophan phosphorescence study.
• Phosphate backbone neutralization increases duplex DNA flexibility: A model for protein binding
• Molecular dynamics study of time-correlated protein domain motions and molecular flexibility: cytochrome P450BM-3.
• Molecular mechanical studies of DNA flexibility: Coupled backbone torsion angles and base-pair openings
• A stereochemical approach to pyranose ring flexibility: its implications for the conformation of dermatan sulfate.