Proton NMR studies of manganese ion binding to tRNA-derived acceptor arm duplexes.
AUTOR(ES)
Ott, G
RESUMO
Several RNA duplexes corresponding to the acceptor arms of different tRNAs have been analyzed with respect to their divalent metal ion binding capability by means of proton NMR spectroscopy using paramagnetic Mn2+ ions as probes. In particular, the role of GU wobble base pairs has been analyzed with reference to their potential for creating metal ion binding sites. It is shown that both the structural modifications induced by GU pairs in the A-RNA geometry and the sequence context seem to affect the metal ion binding capabilities.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=310466Documentos Relacionados
- A novel class of small RNAs: tRNA-derived RNA fragments (tRFs)
- Can SINEs: a family of tRNA-derived retroposons specific to the superfamily Canoidea.
- MIRs are classic, tRNA-derived SINEs that amplified before the mammalian radiation.
- Shaping and reshaping of salmonid genomes by amplification of tRNA-derived retroposons during evolution.
- Distinct subcellular localization of tRNA-derived fragments in the infective metacyclic forms of Trypanosoma cruzi