Purification, crystallization and preliminary X-ray diffraction analysis of disease-related mutants of p97
AUTOR(ES)
Tang, Wai-Kwan
FONTE
International Union of Crystallography
RESUMO
Mutations in the human AAA+ protein p97 cause a disease in humans called IBMPFD. How these mutations affect the structure and function of p97 is unknown. Here, the crystallization of three disease-related mutants of p97 in the presence of ATPγS are reported.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2777050Documentos Relacionados
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